Radiofrequency ablation for Barrett’s esophagus

Description

Barrett's esophagus is the main risk factor for esophageal adenocarcinoma (EAC, with a 50-fold increased risk). Removing the Barrett's mucosa significantly reduces this risk. If neoplastic areas of Barrett's esophagus (i.e., cells that have the potential to become malignant or have already done so) have been previously resected by endoscopy. It is recommended, according to current reflux guidelines, to treat/remove the remaining Barrett's mucosa (even if it is non-dysplastic). A safe and gentle method is radiofrequency ablation (RFA), which involves removing the precancerous mucosa damaged by Barrett's esophagus through gastroscopy (gastric endoscopy) under sedation during an outpatient procedure, while preserving the underlying healthy tissue. The endoscopic procedure lasts approximately 30 to 45 minutes, and patients can generally leave the clinic the same day. In case of occasional mild discomfort, we provide medication to the patients. After 2 to 3 months of treatment, a follow-up gastroscopy is performed to determine if an additional RFA session is necessary.

Added value

Thanks to the technology of the Barrx radiofrequency ablation system offered by its gastroenterology department, the Robert Schuman Hospitals are the only center in Luxembourg capable of treating patients with Barrett's esophagus requiring treatment at the Zithaklinik, thus reducing the relative risk of disease progression from low-grade dysplasia to high-grade dysplasia or EAC by up to 94%.

Status

Fully operational since June 2021.

13
treated patients
7
patients out of 13 completely cured
Dr Steffen Walia Mohan
Gastroenterology, hepatology and endoscopy
"Our project offers considerable added value by providing an innovative approach to the treatment of Barrett's esophagus. By utilizing the Barrx radiofrequency ablation technology, we are able to significantly reduce the risk of progression to esophageal adenocarcinoma, offering patients a safe and effective solution with results that can achieve up to a 94% reduction in the relative risk of disease progression."

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